Upcoming Billion-Dollar Businesses of 2025
Top AI Startups Poised for $1 Billion Valuation by 2025
A list of the top 25 AI-focused venture-backed startups in the U.S., predicted to reach or exceed a $1 billion valuation by 2025, has been compiled by Forbes in partnership with TrueBridge Capital Partners.
The list includes a diverse range of companies, from well-known leaders like OpenAI, Anthropic, xAI, Scale AI, Databricks, and emerging companies such as AcuityMD. Here are some of the key players:
- AcuityMD: An AI-powered MedTech platform that helps medical device manufacturers find the right physicians based on the patients they treat using de-identified data.
- Rogo: A chatbot designed to assist junior bankers with time-consuming tasks like crunching numbers, preparing presentations, and managing spreadsheets.
- Gamma: AI-powered software that can create slick presentations, websites, or social media posts from raw text, documents, or existing decks.
- David AI: A company that supplies voice audio in 15 languages to major tech firms, helping them build smarter AI models capable of understanding speech.
- Basis: AI accounting software that streamlines data entry tasks like transferring information from receipts.
- Collate: A startup aiming to automate the paperwork required for life sciences companies, such as that for clinical trials and FDA approval.
- Apex: Offers a standardized satellite that buyers can customize with their own sensors and instruments for launching into low-Earth orbit.
- Braintrust: An all-in-one command center for testing and monitoring AI-powered apps.
- Agentio: A marketplace of creators for brands to easily find influencers for ad campaigns.
- Forterra: A startup that retrofits more than 50 types of vehicles to drive themselves, including transit buses and military convoy trucks.
- Motif: Software used by architects for designing buildings and complex structures while collaborating with one another in real time.
- LiveKit: Provides the technical back end to enable real-time audio and video for various applications, including 25% of 911 emergency calls in the U.S.
- Nominal: Sells software that collects and analyzes the results of trials of aircraft and other hardware.
- Reflection AI: Aims to build a "superintelligence" that can write and maintain code.
- Decart: An AI lab aiming to rival OpenAI, Anthropic, and Google, using AI to automate various tasks for businesses.
- Reducto: AI software that turns messy documents into clean, usable data.
- Krea: A design tool built by a team of musicians, poets, designers, and videographers, offering AI models for visual artists.
- Browserbase: Aims to change how we interact with the internet entirely by using AI to perform tasks instead of browsing.
- Assort Health: Sells a text-to-voice AI chatbot to search physicians' calendars and match their openings with the type of appointment required.
- Stackblitz: Offers a product called Bolt, which allows people to build apps just by typing in a description.
Other startups on the list include Assort Health, Basis, Braintrust, Browserbase, Collate, David AI, Decart, Forterra, and Gamma. Notably, Loyal, a startup developing drugs that could delay aging by targeting metabolic and hormonal imbalances, is also on the list, with their first beef-flavored longevity pill potentially hitting the market by 2026.
The list of 25 venture-backed startups most likely to reach a $1 billion valuation in 2022 is dominated by AI-focused companies. These companies have collectively raised over $1 trillion in venture funding in 2025, with the U.S. receiving 85.5% of this funding, reflecting the massive capital flow toward these high-value ventures and their rapid valuation growth.
Graphite, a startup developing an AI assistant for code reviews, is one of the companies on the list. Their lead investors include Accel, Andreessen Horowitz, and Homebrew. Current-year revenue estimates for Graphite, Krea, Lead, LiveKit, Loyal, Motif, Nominal, Reducto, Reflection AI, Rogo, Rox, Stackblitz, and Stan are $2 million, $5 million, $170 million, $5 million, $0, $0, $1 million, $0, $0, $2 million, $0, $0, $4 million, and $25 million respectively.
The exact full list of 25 startups is generally curated by venture and market research firms like Forbes and CB Insights, but is not fully enumerated in the available data. However, consensus points to these companies being among the forefront based on their funding, innovation, and market impact.
- The AI-powered startup, Graphite, focusing on code reviews, is poised to reach a $1 billion valuation, with leading investors such as Accel, Andreessen Horowitz, and Homebrew.
- In the realm of business finance, David AI, a supplier of voice audio for major tech firms, is capitalizing on technology to build smarter AI models, contributing to the sector's extensive growth.
