Transforming Biocatalytic Procedures: FromInitial Concept to Large-Scale Industrial Application
Aminoverse, a Dutch start-up company, is making waves in the world of pharmaceuticals, flavors and fragrances, and agrochemicals. With a unique strategy that increases success chances by a staggering 10-fold and reduces R&D spend by up to 75%, Aminoverse has quickly become a go-to partner for over 50 global companies.
Established in 2018, Aminoverse reached profitability just 3.5 years later, an impressive feat achieved without venture capital funding. The company's success is built on a team of 20 interdisciplinary professionals who foster close collaboration with clients through weekly updates and open communication.
In 2021, Aminoverse launched its product-based business with hydroxylation enzyme kits, allowing customers to test enzymes within days and make time-sensitive decisions during route scouting. But what makes enzymes so revolutionary?
Enzymes, naturally occurring proteins, adapt to virtually all chemical targets due to their broad substrate and reaction spectra. They are valued for their ability to make processes more efficient, cut energy use, raw material costs, and waste, boosting profitability or enabling new products. Enzymes also have innately high regio- and stereoselectivity, ensuring precise reactions and purer molecules.
Aminoverse's approach integrates wet lab, biophysics, and cutting-edge AI to discover and design optimal enzymes. The company offers a range of services beyond research, including end-to-end support from the initial idea to industrial application of biocatalytic processes. They identify the right enzyme, define suitable production conditions, optimize biocatalysts by enzyme engineering, develop robust assays, and supply off-the-shelf enzyme kits for immediate screening.
Moreover, Aminoverse offers AI-augmented workflows (EnzyNAV AI, EnzyMAP AI, and EnzyREC AI) for enzyme discovery, optimization, and design. Enzyme immobilization allows the recycling of the biocatalyst and thus reduction of cost of goods, crucial for the production of compounds with a value below 100 $/kg.
Aminoverse aims to be a turn-key solution provider, supporting customers from initial idea to industrial application. As a client-centric enzyme-dedicated Contract Research Organization (CRO), they operate on a fee-for-service model, with clients retaining full IP rights and no royalties.
Looking to the future, Aminoverse aims to continuously refine AI algorithms, streamline wet lab workflows, expand enzyme kits, and eventually design enzymes entirely from scratch (de novo design). The company's ultimate goal is to become the go-to partner for everything about enzymes, revolutionizing industries one enzyme at a time.
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